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Parkinson’s Disease (PD), Lewy Body Dementia (LBD), and Shy-Drager Syndrome (Multiple System Atrophy-MSA) can now be diagnosed by a simple skin biopsy that is 95% to 99% accurate. For years, our family has found that the cause of my father’s skin issues were the cause of his diagnosis. Through research, meeting with dozens of doctors and personal experience we have found that a mite caused his skin condition. Mites cause spinal injury, reduced gut motility, lack of smell, and sleep issues. Researchers have conducted little study on acariasis, an infestation caused by mites, in the human body, where mites have been reported to attack the urinary, otic, pulmonary, intestinal, oral (anaphylaxis), and vaginal systems. Brain cells start dying off due to abnormal alpha-synuclein (Lewy bodies) causing the clumping in Nerve cells resulting in the symptoms of Parkinson’s Disease. A team of researchers at the University of Texas at Arlington have found hard evidence of horizontal DNA transfer, which is the swapping of genetic material between non- mating species - between some parasites and their vertebrate hosts. We believe that a research study could prove our theory that alpha-synuclein is turning abnormal after infestation from a mite.
Seborrheic dermatitis is seen in males 3% of the time and 2.6% of the time in females [3], but the prevalence of seborrheic dermatitis in Parkinson’s Disease is as high as 52%-59% [4]. Owners of animals report that infestation with the cheyletiella mite has a resemblance to cradle cap(seborrheic dermatitis) in kids, a bit flaky and dry scalp[5]. Seborrheic dermatitis is a top disease associated with Mite infestation per Malacards.org. Rabbits affected with the cheyletiella mite may show varying degrees seborrheic lesions with dry or oily scales (very dandruffy) with or without papular eruption[6]. “Seborrheic dermatitis is considered to occur as a premotor feature of PD referable to dysregulation of the autonomic nervous system (Ravn, Thyssen, & Egeberg, 2017)[7].” Seborrheic dermatitis could serve as an early disease marker of PD [7].
Who wants to go around telling people that? One of my family members was mortified at the thought of confessing to his neurologist that we suspected mites were the culprits behind his illness. But things took a hilarious turn when he found out that his neurologist was testing him for syphilis instead! Suddenly, our mite problem didn't seem so bad after all. At least it wasn't the "s-word" we had to worry about!
-Dementia the Overlapping Diseases - AD, LBD, PD "..A-syn (a- synuclein) was first found in association with Alzheimer's disease (AD) plaques several years before being linked to PD or Lewy body formation. Nowadays, a large subset of AD patients (~50%) is well recognized to co-exhibit significant a-syn Lewy body pathology (Marsh & Blurton-Jones, 2012).” [1]. According to Dr. James Galvin, a professor of neurology at the University of Miami Miller school of Medicine has found that no distinctive sign or symptom distinguishes dementia with Lewy body from Parkinson’s dementia; however, time of onset is often used to determine which LBD subtype is present[2].
-Seborrheic dermatitis is seen in males 3% of the time and 2.6% of the time in females [3], but the prevalence of seborrheic dermatitis in Parkinson’s Disease is as high as 52%-59% [4]. Owners of animals report that infestation with the cheyletiella mite has a resemblance to cradle cap(seborrheic dermatitis) in kids, a bit flaky and dry scalp[5]. Seborrheic dermatitis is a top disease associated with Mite infestation per Malacards.com. Rabbits affected with the cheyletiella mite may show varying degrees seborrheic lesions with dry or oily scales (very dandruffy) with or without papular eruption[6]. “Seborrheic dermatitis is considered to occur as a premotor feature of PD referable to dysregulation of the autonomic nervous system (Ravn, Thyssen, & Egeberg, 2017)[7].” Seborrheic dermatitis could serve as an early disease marker of PD[7].
-Heiko Braak, MD hypothesized that sporadic PD is caused by an unknown pathogen that enters the body via the nasal cavity and is swallowed where it soon reaches the gut initiating Lewy pathology in the nose and digestive tract.
-Difficulty in failing to cure a Cheyletiella mite infestation can be due to them living intranasally per the article “Dandruff in Dogs” on the website lowchenaustralia.com.
-Mites have caused cases of human acariasis of vaginal systems, pulmonary, intestinal, urinary, otic, and oral (anaphylaxis)[7a].
-PD is a systemic disease [8]. Cheyletiella mites cause systemic illness[9]. Mites carry bacteria, disease, fungus and can dissolve tissue giving rise to an increased risk of breaking the sinus brain barrier and also taking on your DNA so it would be difficult to detect.
-“Scientists have devised a vaccine that has shown promise in the treatment of Psoriasis and cat allergies, as well as in the prevention of Alzheimer's disease(Sandoiu, 2017).” [10] Psoriasis is one of the top diseases associated with Mite Infestations. [11] From our experience, this is no coincidence. People with Psoriasis are 38% more likely to develop PD [12]. "House dust mite induced asthma exacerbates AD by increasing amyloid beta accumulation and neuroinflammation[12a]." Chitin, a major part in the exoskeleton of arthropods, has been reported in the AD brain [12b, 12c,12d] and the PD brain[12e].
-Cheyletiella and Demodex are in the order of trombidiformes, The greek root "Trom" refers to tremors or trembling.
-The World Renowned Expert on Autoimmune Diseases, Dr. Steven Philips acquired his autoimmune diseases from a spider bite. Parkinson's disease and Alzheimer's disease are classified as autoimmune diseases, and individuals who have one autoimmune disease are 25% more likely to develop another[13].
-Lastly, did you know that there is not a lot of research on mites and humans? Searching through medical journals all over the world studies have been uncovered, both in animals and humans. Some of the most important studies come from the studies of rabbits. Rabbits as models of human infectious disease have given researchers valuable insights into pathology that is very similar to human patients[14]. Multiple family members also had similar symptoms as my father over the years. My mother and I were his main caregivers.
Skin Issues Seborrheic Dermatitis is a well known symptom of PD. Patients with Rosacea have a 71% higher risk for PD [15]. Demodex mites are a known cause of rosacea. Parkinson’s Disease causes increase secretion of sebum, Mites feed on sebum and skin cells. Parkinson’s Disease patients have a much higher risk of Melanoma[16]. My father was diagnosed with melanoma prior to his diagnosis and the white scar on the picture below is where he had it removed. Incidentally, after my father’s diagnosis my mother was diagnosed with melanoma in situ (melanoma cancer cells in top layer of skin) in the area where she was bitten.
*Top Diseases Associated with Mite Infestation
Seborrheic Dermatitis
Psoriasis
Atopic Dermatitis/Eczema
Allergic Disease
Blepharitis
Eye Disease
Bronchiolitis
Myiasis
Parasitic Helminthiasis Infectious Disease
Dermatitis
*information obtained from MalaCards Human Disease Database www.malacards.org/card/ mite_infestation
Is it a Coincidence Skin Disease Increasing and Early Parkinson Diagnosis Increasing by 50%? In Dr. Alice M. Jeromin’s veterinarian practice, she actually sees more animal cases of “walking dandruff” than fleas and believes it has been caused by safer, newer, more effective flea control, that the majority do not eradicate the Cheyletiella mite[17]. Asymptomatic carriers in the household may include dogs, cats and rabbits[18]. Only two humans suspected their pets were the cause of their dermatitis in a study of 37 patients diagnosed with cheyletiellosis[19]. A slow recognition occurs due to a failure to recover the mite from humans[20]. In an article published on October 22, 2020 on Blue Cross/Blue Shield’s website, a review of records showed that in 2017 adults between the ages of 30 and 64 had a 50% increase in diagnosis of Parkinson’s Disease in a span of 5 years. During this time, there has been a dramatic increase in revenue for products like Apoquel and skin disease medicines for humans and pets that treat the symptoms but do not cure the disease.
Reduced Smell A reduced sense of smell is often an early sign of PD. Mites, dander, allergic rhinitis, an allergic reaction to airborne pollen, and other irritants leads to sneezing, runny nose and a lack of smell[21].
Hearing Loss is an early symptom of PD. My father had hearing loss and his hearing fluctuated tremendously. We believe this fluctuation was caused by infestation level.
Hearing Loss can be caused by ear mites due to the mite damaging the ear canal because it was left untreated[22]. If there is an ear mite infestation in the ear, it can turn into a serious ear disease called otitis external which if untreated it can damage the ear which could permanently affect the animal’s hearing and sense of balance[23].
Do You Have Eye and Urinary Issues? Within days of my father having his lower left eye lid cauterized after a dozen eye infections, he was unable to pee and was taken to ER. 18% of people with PD have foreign body sensation, itching, blurred vision, blepharitis or dry eye, only 3% of the general population experiences this [24]. Urinary difficulties occur in 30-40% of people with PD [25]. His eye doctor was 95% sure it was a mite causing his eye issues. An over the counter eye drop with Omega 3's was prescribed daily by his eye doctor. As a result, he never had an eye infection again.
Spinal Injury As mentioned earlier a lot of research has been conducted on animals. As PD progresses, it is very common to see changes in the spine (26). Rabbits affected with cheyletellosis may have concurrent disease such as spinal pain that turns into Spinal injury once the animal changes from a carrier state to diseased[6]. It has been found that rabbits with spinal disease/spinal pain can result in reluctance to exercise, quiet, unresponsive demeanor, reduced gut motility, and aggression towards companions or owners[27].
Sleep disorders are Widespread in Parkinson’s. Sinus and nasal problems are often the cause of sleep apnea[28]. Nasal allergies can lead to sleep disturbances [29].Cheyletiella mites cause sinus problems[17]. Commonly mites are more active in the nighttime when they can cause severe itching[30].
If it is Contagious, Why Does only one person have Dementia in the household? Significant bite reactions in a household are usually experienced only in one person[31]. If a cat is infested with the cheyletiella mite, not all person with close contact or in an infested household are affected, some may be asymptomatic[17, 20, 32]. "The zoonotic fur mite Cheyletiella parasitovorax may facilitate a dermatophyte infection (examples ringworm, nail infection, athlete's foot).(Overgaauw, Avermaete, Mertens, Meijer, & Schoemaker, 2017,pgs 106-109) [33]” Mites usually attack young, old and immunocompromised. Spouses have a 1.6 times greater risk for dementia- study taken from Cache County [34] where my father and mother had a second home for many years and a close family member was a Emergency Room physician who lived and worked in that county. Neurosurgeons die from Alzheimers at almost 2.5 times higher rate than the general population [35] Dr. Donald Calne, director of the Neurodegenerative Disorders Centre at the University of B.C. Hospital, has found that PD can occur in groups of people, such as workers or teachers who live close to each other [36].
What? Caffeine Kills Mites? And Decreases Lewy Bodies
Caffeine, a natural Acaricide, is inversely Associated with Lewy bodies. Acaricides are pesticides used to kill ticks and mites. In The Rush Memory and Aging Project (MAP), during an examination of deceased participants in the study, it was found that caffeine was inversely associated with Lewy bodies[37]. Caffeine can also tame Parkinson’s Disease Tremors[38].
Omega 3’s for PD and Mites
Multiple studies have shown beneficial effects of Omega 3’s and how it protects against Parkinson’s Disease[39,40] . Omega-3's help keep the dandruff away and also slows cognitive decline and atrophy when taken with b vitamins. While reading “Dandruff in Dogs” on the website lowchenaustralia.com, an article about the cheyletiella mite, it advised increasing a daily intake of essential fatty acids such as Omega 3’s as “A fish a day helps keep Dandruff Away”[41]. http://www.lowchensaustralia.com/health/dandruff.htm
I was chronically ill for many years and found out after my father and a young relative got sick, that it was a mite causing our families illness. One of the interesting treatments in helping us get better was omega 3’s. I drank a green smoothie with flax seed (omega 3’s) to get better, the young relative took a multi-vitamin and high doses of fish oil (omega-3’s) to get better, and my father used daily omega-3 eye drops to avoid any eye infections. My father’s last ophthalmologist was 95% sure his eye issues were caused by a mite, the other doctors said he had blepharitis which is known to be caused by mites. Due to fish oil being a blood thinner, he never took high doses of omega-3’s as he was on a blood thinner. In the fall of 2019, my parents and I traveled to Italy. While on tour, the tour guide mentioned that Italy had lost more than a 1/3 of its population due to Black Death. The tour guide said that many Italians who lived on the coast were spared as they mostly lived on a diet of Fish (Omega 3’s) as the main carrier of black Death was fleas. Wow! Omega 3’s (Flax seed) was what I had taken to get well and our young relative’s decreasing irregular heartbeats and other symptoms went to normal while taking Omega 3’s (Fish Oil). I thought there was a connection, and later figured out it to be a mite. As we know, mites are also carriers of disease.
Senile Hemangioma, Mites, N-Acetyl Cysteine (NAC), Propranolol and Parkinson’s Disease
At the end of October 2020, I flew across the United States to meet with a professor of dermatology who is also an author/co-author of a number of articles about the Cheyletiella Mite. He said the red moles previously diagnosed as cherry angiomas/ senile hemangiomas could be caused by the Cheyletiella mite. These bullous arthropod bite reactions (BABR) occurs in sensitive individuals with hypersensitivity immune reaction to insect saliva[42]. Bullous Eruptions/ Senile hemangiomas was a symptom of my Families Illness (teenagers, adults and seniors). Hemangiomas are a type of cherry/senile angiomas. The most common treatment for skin Hemangiomas for babies is Propranolol, a beta blocker. [43] The beta blocker shrinks hemangiomas, even huge ones until they are barely visible. Propranolol also inhibits parasite growth in the blood stage[44]. Propranolol is currently prescribed to reduce tremors in people with PD.
A very common definition of Senile is a Person's Loss of Mental Faculties. I acquired senile hemangiomas all over my stomach when I was really sick and infested by the mite. Later, I was diagnosed with three hemangiomas in my liver, one being the size of a grapefruit (10cm). I told my doctor numerous times that whatever was in my sinuses was causing my illness. When my sinuses would drain down the back of my throat, I would have pain in my liver where the largest hemangioma was. The Cheyletiella mite lives in the sinuses and is very difficult to get rid of in your sinuses. My father also had chronic sinus issues. The dermatologist advised to get rid of the illness, he recommended 600mg of NAC (N-acetyl cysteine) three times a day. I was shocked that he recommended NAC - NAC is a precursor to the most important antioxidant in the brain, glutathione. I had remembered that the diagnosis back in the 1980’s for Parkinson’s was due to the lack of glutathione in the brain. Glutathione is the most important antioxidant in the brain. In a 2016 pilot study, a team at Thomas Jefferson University discovered that NAC can help improve symptoms and dopamine function in Parkinson’s patients[45]. NAC is used for the treatment of intestinal parasitic infections[46]. NAC also thins your blood.
After years of researching, I found that a team of researchers from the University of Texas at Arlington have found evidence of horizontal DNA transfer, which is the swapping of genetic material between non-mating species, including certain parasites and their vertebrate hosts. This discovery is significant because it could make it harder to identify the source of infestation and diagnose the causes of dermatitis in humans, as the similarity of DNA between mites and their hosts could complicate the process. Abnormal Alpha-synuclein has been implicated in Parkinson's disease, Lewy body dementia, and multiple system atrophy. I believe that a scientific study is needed to confirm if swapping of genetic material between mites and humans could lead to the development of abnormal Alpha-synuclein in humans.
I believe that parasite swapping DNA should also be researched with all types of autoimmune disease. World renowned autoimmune doctor, Dr. Steven Philips, found that his autoimmune disease was caused by a spider bite. Spiders and mites belong to the class arachnid and are arthropods. Mites have been found in the skin of patients with autoimmune diseases such as psoriasis and lupus[47, 9, 48], and there is a hypothesis that mites may cause the immune system to overreact and attack the body's own tissues[49]. Additionally, research has shown that certain mites can produce allergens that can trigger autoimmune responses in susceptible individuals[49]. Further research is needed to fully understand the link between mites and autoimmune diseases.
Does this look familiar? Sometimes identified as a Senile Hemangioma
By using human healthy lab grown skin, we could test whether the alpha-synuclein turns abnormal (lewy bodies) after a mite bite. The Syn-one test is a skin test[50] that could be used to determine if alpha-synuclein is abnormal after a bite. This test can identify if you have Lewy bodies, but is unable to distinguish if you have PD, LBD, or MSA. The test is 95-99% accurate. The skin biopsy is taken from the back[50], a place where mites like to attack. Are you interested in verifying the Connection? An Italian team led by Michele De Luca, at the University of Moderna, has successfully grown in his laboratory genetically modified skin[51]. This skin could be tested to see if a mite infestation would turn the alpha-synuclein abnormal in that area, we can verify the connection. It is known that the bites of parasites can swap genetic material causing mutations[52]. The cheyletiella mite has caused severe illness with systemic symptoms (affecting the whole body- alikeness to Multi System Atrophy) to mild dermatitis in humans[9].
Lewy bodies cause PD, LBD, and MSA. Over the years, my father had seborrheic dermatitis, itching, acute rosacea, hearing loss, senile hemangiomas, melanoma, 14 eye infections in his left eye, sinus problems, urinary infections, urinary retention, blood pressure drops, muscle weakness, tremors, memory loss and sleep issues. He was diagnosed with the Alzheimer's gene and years later diagnosed with Lewy body Dementia. Many studies have found that people with PD had decreased smell in their left nostril.
In Loving Memory of my Father. Thank you to my amazing friends and family for your support.
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"All truth passes through three stages.
First, it is ridiculed.
Second, it is violently opposed.
Third, it is accepted as being self evident."
Arthur Schopenhauer